So as we get ready for Halloween and all those cute little goblins and princesses let’s tackle the million dollar question: Does PGS improve IVF outcomes? The lunch debate between Munne and Hughes at the ASRM sought to discuss that issue. Basically, Dr. Munne presented evidence that in their hand IVF outcomes are better and miscarriage rates are lower. However, the improvement was modest and not the amazingly high pregnancy rates that one would predict. Dr. Munne also criticized the recent article from Europe in the New England Journal of Medicine...
mercredi 31 octobre 2007
dimanche 28 octobre 2007
As Gandalf said to Frodo “Is it safe?” That is certainly an important question to examine. If we pursue PGD we certainly do not want to shoot ourselves in the foot.First of all, how could PGD create a problem? Well there are several steps that could cause potential problems. The embryo biopsy could result in damage to the remaining cells in the embryo. The removal of 1/8th of the cells in the embryo could alter the development of the embryo. The biopsy of the embryo could result in an embryo that is less tolerant of cryopreservation (freezing)....
samedi 27 octobre 2007
What a difference a couple of weeks can make. Several weeks ago the Red Sox seemed doomed to another “close but no cigar” type of season and here they are in the World Series. Over October 12-16th the annual meeting of the ASRM was here in Washington DC. It is tough to have the meeting in one’s hometown as working while attending the daily meeting can be problematic…although not as problematic as going out at night to parties and then working the next AM. However, as a fairly boring the Eagle Scout straight arrow nice guy who prefers to be in bed...
mardi 9 octobre 2007
On the INCIID bulletin board I am often asked to comment on how many embryos to transfer. It amazes me that anyone would value the opinion of the cyber-RE over their actual RE. This decision is too important to just gloss over and give it only a passing thought. Transfer too many and we have to deal with twins…or worse. Transfer too few and the next thing you know the patient is requesting records to zip off to the RE down the street. How easy things...
vendredi 5 octobre 2007
Readers of this blog may recall that my MacBook Pro was stolen from my car while it was parked in my driveway on a residential street in Bethesda, MD. Like a complete idiot I had left it in my unlocked car overnight and like an even bigger idiot I had not password protected the computer (huge gasp of shock from the reader). Fortunately, the computer was fully backed up just 48 hours earlier and I successfully restored all of my files (including the photo of me in my Boy Scout leader uniform which I have mercifully deleted from the blog).Last night...
mercredi 3 octobre 2007
All doctors have different styles and as a patient I truly believe that you need to be comfortable with your physician. There is a level of trust that must exist between patient and physician and this relationship goes both ways. Some patients want to abdicate all decision making responsibility and others want to agonize over every minor point sending their RE emails several times a day.Overall, I think that I have a pretty good rapport with my patients and thus I am puzzled by the fact that twice in as many weeks I have had patients comment to...
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