
Usually we urge patients to pursue elective single embryo transfer (eSET) if it is their first cycle of stimulated IVF and they are < 35 years old and embryo quality is very good to excellent. However, as many patients/couples view twins as an acceptable and even desirable outcome it is hard to sell eSET to many of them.
In this case, the couple had been through a lot but was open to eSET. I was very happy when I saw the first beta level but figured it was just a really healthy singleton. Then came the first pregnancy sonogram and I saw a single gestational sac with two yolk sacs. Oh well. Follow-up sonograms demonstrated that the twins were not in a single sac which would have made the pregnancy a much higher risk endeavor. Still identical twins were not on our radar screen as the rate of identical twinning is usually only 1-2%.
So in spite of eSET, not all pregnancies will be singletons but as I really can't transfer less than one embryo we are stuck with a small risk of twins no matter what....
Still, as I tell my patients at the time of ET, I don't babysit and I don't change diapers anymore..
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